DrugRepV Browse Page


DrugRepV browse page allows user to take a glance of the particular antiviral agent.Fields in the webpage is hylerlinked ot various external repositories like DrugBank, PubChem, Clinicaltrials.gov,and PubMed.User can explore the biological, Clinical, Chemical, and Structural details of every repurposed drug candidate.By clicking on the table header arrows, user can sort entries in ascending or descending order.


Total number of Records for Renilla luciferase assay are 51




DrugRepV_ID Antiviral Name
Drug type
Primary Indication
Secondary Indication
Strain
Pathways
Assay
Activity
Clinical Status
 References
DrugRepV_0338Niclosamide
Antiparasitic products, Insectisides and Repellents
Tapeworm and intestinal fluke infections | Helminthiasis
Ebola virus
Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus
NA
Renilla luciferase assay
Decrease (50 %)
Approved
27622822
DrugRepV_0339Mebendazole
Antiparasitic products, Insectisides and Repellents
Helminthiasis (Enterobius vermicularis (pinworm), Trichuris trichiura (whipworm), Ascaris lumbricoides (common roundworm), Ancylostoma duodenale (common hookworm), Necator americanus (American hookworm) in single or mixed infections)
Ebola virus
Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus
NA
Renilla luciferase assay
Decrease (50 %)
Approved, Vet approved
27622822
DrugRepV_0340Amiodarone
Cardiovascular agents
Anginal and Arrhythmia
Ebola virus
Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus
NA
Renilla luciferase assay
Decrease (50 %)
Approved
27622822
DrugRepV_0341Procainamide
Cardiovascular agents
Ventricular arrhythmias
Ebola virus
Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus
NA
Renilla luciferase assay
Decrease (50 %)
Approved
27622822
DrugRepV_0342Azithromycin
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus
NA
Renilla luciferase assay
Decrease (50 %)
Approved
27622822
DrugRepV_0343Chlortetracycline
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus
NA
Renilla luciferase assay
Decrease (50 %)
Approved
27622822
DrugRepV_0344Benztropine
Nervous System
Parkinson disease
Ebola virus
Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus
NA
Renilla luciferase assay
Decrease (50 %)
Approved
27622822
DrugRepV_0345Chloroquine
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus
NA
Renilla luciferase assay
Decrease (50 %)
Approved
27622822
DrugRepV_0346Hydroxychloroquine
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus
NA
Renilla luciferase assay
Decrease (50 %)
Approved
27622822
DrugRepV_0347Amodiaquine
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus
NA
Renilla luciferase assay
Decrease (50 %)
Approved
27622822
DrugRepV_0348Bepridil
Cardiovascular agents
Hypertension and angina
Ebola virus
Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus
NA
Renilla luciferase assay
Decrease (50 %)
Approved
27622822
DrugRepV_0349Vincristine
Antineoplastic and Immunomodulating Agents
Cancer (Acute leukemia |Hodgkin's and non-Hodgkin's lymphoma |Neuroblastoma |Rhabdomyosarcoma |Ewing's sarcoma |Wilms' tumor | Multiple myeloma | Chronic leukemias | Thyroid cancer | Brain tumors)
Ebola virus
Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus
NA
Renilla luciferase assay
Decrease (50 %)
Approved
27622822
DrugRepV_0350Prochlorperazine
Nervous System
Nausea | Vomiting | Schizophrenia
Ebola virus
Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus
NA
Renilla luciferase assay
Decrease (50 %)
Approved
27622822
DrugRepV_0351Paroxetine
Nervous System
Major depressive disorder (MDD) | Panic disorder | Obsessive-compulsive disorder (OCD) | Social anxiety disorder (social phobia) | Generalized anxiety disorder (GAD) | Post-traumatic stress disorder (PTSD) | Premenstrual dysphoric disorder (PMDD)
Ebola virus
Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus
NA
Renilla luciferase assay
Decrease (50 %)
Approved, Investigational
27622822
DrugRepV_0352Clomiphene
Genito Urinary System and Sex Hormones
Polycystic ovary syndrome
Ebola virus
Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus
NA
Renilla luciferase assay
Decrease (50 %)
Approved
27622822
DrugRepV_3061Abamectin
NA
Helmintic infection
Chikungunya virus
CHIKV-Rluc
NA
Renilla luciferase assay
No significant effect (No significant effect %)
Terminated
26752081
DrugRepV_3062Amphotericin B
Antiinfectives For Systemic Use
Fungal infection
Chikungunya virus
CHIKV-Rluc
NA
Renilla luciferase assay
No significant effect (90 %)
Approved
26752081
DrugRepV_3063Berberine
NA
Parasitic and fungal infection
Chikungunya virus
CHIKV-Rluc
NA
Renilla luciferase assay
No significant effect (No significant effect %)
Approved
26752081
DrugRepV_3064Bromocriptine
Nervous System
Parkinson disease
Chikungunya virus
CHIKV-Rluc
NA
Renilla luciferase assay
No significant effect (3 %)
Approved
26752081
DrugRepV_3065Cerivastatin
Cardiovascular agents
Rhabdomyolysis
Chikungunya virus
CHIKV-Rluc
NA
Renilla luciferase assay
No significant effect (10 %)
Approved
26752081
DrugRepV_3857Clomiphene
Genito Urinary System and Sex Hormones
Polycystic ovary syndrome
Ebola virus
Mayinga
NA
Renilla luciferase assay
Decrease (100 %)
Approved
27490565
DrugRepV_3858Enclomiphene
NA
Male hypogonadism
Ebola virus
Mayinga
NA
Renilla luciferase assay
Decrease (100 %)
Investigational
27490565
DrugRepV_3859Zuclomiphene
NA
NA
Ebola virus
Mayinga
NA
Renilla luciferase assay
Decrease (100 %)
NA
27490565
DrugRepV_5987Castanospermine
Antiviral
Dengue and Parainfluenza
Dengue virus
16681-Replicon
Pathway
Renilla luciferase assay
Decrease
Experimental
15994763
DrugRepV_6374(2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide
NA
NA
Dengue virus
NA
Pathway
Renilla luciferase assay
Decrease (50 %)
NA
24083834
DrugRepV_6375(2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-3-methyl-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide
NA
NA
Dengue virus
NA
Pathway
Renilla luciferase assay
Decrease (50 %)
NA
24083834
DrugRepV_6376(2S)-6-amino-2-[(2S)-2-[(4-{[(5Z)-3-butyl-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]-5-carbamimidamidopentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide
NA
NA
Dengue virus
NA
Pathway
Renilla luciferase assay
Decrease (50 %)
NA
24083834
DrugRepV_6377(2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-3-cyclopentyl-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide
NA
NA
Dengue virus
NA
Pathway
Renilla luciferase assay
Decrease (50 %)
NA
24083834
DrugRepV_6378(2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-3-cyclohexyl-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide
NA
NA
Dengue virus
NA
Pathway
Renilla luciferase assay
Decrease (50 %)
NA
24083834
DrugRepV_6379methyl 2-[(5Z)-5-[(4-{[(1S)-1-{[(1S)-5-amino-1-{[(1S)-1-carbamoylpentyl]carbamoyl}pentyl]carbamoyl}-4-carbamimidamidobutyl]carbamoyl}phenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]hexanoate
NA
NA
Dengue virus
NA
Pathway
Renilla luciferase assay
Decrease (50 %)
NA
24083834
DrugRepV_6380(2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-4-oxo-3-(prop-2-en-1-yl)-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide
NA
NA
Dengue virus
NA
Pathway
Renilla luciferase assay
Decrease (50 %)
NA
24083834
DrugRepV_6381(2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-3-(2-hydroxyethyl)-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide
NA
NA
Dengue virus
NA
Pathway
Renilla luciferase assay
Decrease (50 %)
NA
24083834
DrugRepV_6382(2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-3-(4-methoxyphenyl)-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide
NA
NA
Dengue virus
NA
Pathway
Renilla luciferase assay
Decrease (50 %)
NA
24083834
DrugRepV_6383(2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-3-(4-chlorophenyl)-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide
NA
NA
Dengue virus
NA
Pathway
Renilla luciferase assay
Decrease (50 %)
NA
24083834
DrugRepV_6384(2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-3-[(4-methoxyphenyl)methyl]-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide
NA
NA
Dengue virus
NA
Pathway
Renilla luciferase assay
Decrease (50 %)
NA
24083834
DrugRepV_6385(2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-3-[(4-chlorophenyl)methyl]-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide
NA
NA
Dengue virus
NA
Pathway
Renilla luciferase assay
Decrease (50 %)
NA
24083834
DrugRepV_6386(2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-4-oxo-3-(2-phenylethyl)-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide
NA
NA
Dengue virus
NA
Pathway
Renilla luciferase assay
Decrease (50 %)
NA
24083834
DrugRepV_6387(2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide
NA
NA
Dengue virus
NA
Pathway
Renilla luciferase assay
Decrease (50 %)
NA
24083834
DrugRepV_6388(2S)-6-amino-2-[(2S)-2-[(4-{[(5Z)-3-butyl-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]-5-carbamimidamidopentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide
NA
NA
Dengue virus
NA
Pathway
Renilla luciferase assay
Decrease (50 %)
NA
24083834
DrugRepV_6389(2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-3-cyclopentyl-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide
NA
NA
Dengue virus
NA
Pathway
Renilla luciferase assay
Decrease (50 %)
NA
24083834
DrugRepV_6390(2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-3-(2-hydroxyethyl)-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide
NA
NA
Dengue virus
NA
Pathway
Renilla luciferase assay
Decrease (50 %)
NA
24083834
DrugRepV_6391(2S)-6-amino-2-[(2S)-2-[(4-{[(5Z)-3-benzyl-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]-5-carbamimidamidopentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide
NA
NA
Dengue virus
NA
Pathway
Renilla luciferase assay
Decrease (50 %)
NA
24083834
DrugRepV_6392(2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-3-[(4-chlorophenyl)methyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide
NA
NA
Dengue virus
NA
Pathway
Renilla luciferase assay
Decrease (50 %)
NA
24083834
DrugRepV_6393(2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-2,4-dioxo-3-(2-phenylethyl)-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide
NA
NA
Dengue virus
NA
Pathway
Renilla luciferase assay
Decrease (50 %)
NA
24083834
DrugRepV_6394(2S)-N-[(4S,7S)-1-amino-7-{[1-(4-{[(5Z)-3-benzyl-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}phenyl)ethenyl]amino}-10-carbamimidamido-5,6-dioxodecan-4-yl]-2-hydrazinylhexanamide
NA
NA
Dengue virus
NA
Pathway
Renilla luciferase assay
Decrease (50 %)
NA
24083834
DrugRepV_6395(2S)-N-[(5S,8S)-1-amino-11-carbamimidamido-6,7-dioxo-8-[(3-{[(5Z)-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]undecan-5-yl]-2-hydrazinylhexanamide
NA
NA
Dengue virus
NA
Pathway
Renilla luciferase assay
Decrease (50 %)
NA
24083834
DrugRepV_6396(2S)-N-[(5S,8S)-1-amino-11-carbamimidamido-8-[(3-{[(5Z)-3-cyclopentyl-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]-6,7-dioxoundecan-5-yl]-2-hydrazinylhexanamide
NA
NA
Dengue virus
NA
Pathway
Renilla luciferase assay
Decrease (50 %)
NA
24083834
DrugRepV_6397(2S)-N-[(5S,8S)-1-amino-11-carbamimidamido-8-[(2S)-2-[(5Z)-5-[(3,4-dimethoxyphenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-3-phenylpropanamido]-6,7-dioxoundecan-5-yl]-2-hydrazinylhexanamide
NA
NA
Dengue virus
NA
Pathway
Renilla luciferase assay
Decrease (50 %)
NA
24083834
DrugRepV_6398(2S)-N-[(5S,8S)-1-amino-11-carbamimidamido-8-(2-{3-[(4-methoxyphenyl)methyl]-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-yl}acetamido)-6,7-dioxoundecan-5-yl]-2-hydrazinylhexanamide
NA
NA
Dengue virus
NA
Pathway
Renilla luciferase assay
Decrease (50 %)
NA
24083834
DrugRepV_6399(2S)-N-[(5S,8S)-1-amino-11-carbamimidamido-8-{2-[(5Z)-3-[(4-methoxyphenyl)methyl]-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]acetamido}-6,7-dioxoundecan-5-yl]-2-hydrazinylhexanamide
NA
NA
Dengue virus
NA
Pathway
Renilla luciferase assay
Decrease (50 %)
NA
24083834
DrugRepV_7092Castanospermine
Antiviral
Dengue and Parainfluenza
West Nile virus
NY 1999-Replicon
Pathway
Renilla luciferase assay
No significant difference
Experimental
15994763